Trilla A, Amymerich M, Giol M, Carné X, Asenjo M A, Rodés J
Centro de Epidemiología, Evaluación, Soporte y Prevención (CEASP), Hospital Clínic, Universidad de Barcelona.
Med Clin (Barc). 2000 Apr 29;114(16):609-13. doi: 10.1016/s0025-7753(00)71377-7.
To identify the Spanish scientific production amongst different areas of clinical knowledge, and to compare it with those of five other European Union countries.
Review of MEDLINE data base, for the period 1993-1997. Search limited to four journals, selected, for 10 different medical specialties (Cardiology, Endocrinology, Infectious Diseases, Gastroenterology-Hepatology, Haematology, Nephrology, Pneumology, Neurology, Oncology, Rheumatology). Articles published by authors from Germany, France, Italy, The Netherlands, Sweden and Spain. Journals included in the Internal Medicine subject classification were independently analysed. Data were also related with several econometric indexes.
A total of 1,763 original articles published by Spanish authors were identified in the journal's sample over the analysed period (2.08 articles per 100 all published articles). Spain contributes to the total achieved by the six European countries analysed with 9.07 articles per 100 published articles. Gastroenterology-Hepatology was the medical specially which has more articles published by Spanish authors (total: 338 articles; 4.15 articles/100 published articles); and Oncology the one with less articles published (1.26 articles/100 published articles). The mean IF value per journal by article is highest for Gastroenterology-Hepatology (4.86 FI/article) and lowest for Pneumology (2.42 FI/article). Spain is the last amongst all six European countries analyzed in Endocrinology, Oncology and Haematology, and second to last in all others except for Gastroenterology-Hepatology (4th place). Mean cost for each article produced by Spanish authors in the analyzed sample was 0.49 US $ according the health expenditures per capita, and 0.07 US $ according the R+D expenditures per capita. Data from the independent analysis of Internal Medicine journals also showed that Gastroenterology and Hepatology is the subspecialty with a higher number of papers published in those journals.
All efforts devoted to improve the quality of Spanish biomedical research, specially in clinical research, had produced positive, but uneven, results, measured by the number and impact factor of original articles published in top ranked biomedical journals. The overall distribution of high impact factor scientific production by specialties is poor when compared to the European Union countries included in the analysis. Those results showed several improvement opportunities. Besides increasing the overall budget for R+D, its is likely that the time has come for backing the highest quality Spanish biomedical research, the one that offers greater and better chances for achieving scientifically valid results, and is published in high impact factor biomedical journals.
确定西班牙在不同临床知识领域的科研成果，并与其他五个欧盟国家进行比较。
回顾1993 - 1997年期间的MEDLINE数据库。搜索限于四种期刊，针对10个不同医学专科（心脏病学、内分泌学、传染病学、胃肠病学 - 肝病学、血液学、肾脏病学、肺病学、神经病学、肿瘤学、风湿病学）进行筛选。分析德国、法国、意大利、荷兰、瑞典和西班牙作者发表的文章。对纳入内科主题分类的期刊进行独立分析。数据还与多个计量经济学指标相关。
在分析期内，在所分析的期刊样本中，共识别出西班牙作者发表的1763篇原创文章（每100篇所有发表文章中有2.08篇）。西班牙每100篇发表文章中贡献了9.07篇，占所分析的六个欧洲国家的总数。胃肠病学 - 肝病学是西班牙作者发表文章最多的医学专科（总计338篇文章；每100篇发表文章中有4.15篇）；而肿瘤学发表文章最少（每100篇发表文章中有1.26篇）。每篇文章的期刊平均影响因子值在胃肠病学 - 肝病学中最高（4.86影响因子/篇文章），在肺病学中最低（2.42影响因子/篇文章）。在所有六个欧洲国家中，西班牙在内分泌学、肿瘤学和血液学方面排名最后，在除胃肠病学 - 肝病学（第4名）之外的所有其他领域中排名倒数第二。根据人均卫生支出，西班牙作者在分析样本中每篇文章的平均成本为0.49美元，根据人均研发支出为0.07美元。内科期刊的独立分析数据还表明，胃肠病学和肝病学是在这些期刊上发表论文数量较多的亚专科。
通过在顶级生物医学期刊上发表的原创文章数量和影响因子衡量，为提高西班牙生物医学研究质量所做的所有努力，特别是在临床研究方面，都产生了积极但不均衡的结果。与分析中纳入的欧盟国家相比，高影响因子科研成果按专科的总体分布较差。这些结果显示了几个改进机会。除了增加研发总体预算外，可能现在是支持西班牙最高质量生物医学研究的时候了，这种研究有更大更好的机会取得科学有效的结果，并发表在高影响因子的生物医学期刊上。
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