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短暂性全面性遗忘症解剖结构的单光子发射计算机断层扫描(SPECT)研究

A SPECT study of the anatomy of transient global amnesia.

作者信息

Warren J D, Chatterton B, Thompson P D

机构信息

Department of Neurology, Royal Adelaide Hospital, South Australia, Australia.

出版信息

J Clin Neurosci. 2000 Jan;7(1):57-9. doi: 10.1054/jocn.1998.0129.

DOI:10.1054/jocn.1998.0129
PMID:10847653
Abstract

This report describes single photon emission tomography (SPECT) evidence of transient, relative hypoperfusion of the right basal ganglia and left temporal lobe in a 60-year-old man studied during the acute phase of classical transient global amnesia (TGA). The findings are interpreted in the light of previous reports indicating that involvement of the right hemisphere or both cerebral hemispheres consistently predicts severe retrograde amnesia, in addition to the typical loss of anterograde memory observed during TGA. These deficits involving the right hemisphere and left temporal lobe may reflect disruption of circuits mediating episodic memory retrieval and memory encoding, respectively.

摘要

本报告描述了一名60岁男性在经典短暂性全面性遗忘症(TGA)急性期接受研究时,单光子发射断层扫描(SPECT)显示右侧基底神经节和左侧颞叶出现短暂性相对灌注不足的证据。鉴于先前的报告表明,除了TGA期间典型的顺行性记忆丧失外,右侧半球或双侧大脑半球受累一直预示着严重的逆行性遗忘,这些发现得到了解释。涉及右侧半球和左侧颞叶的这些缺陷可能分别反映了介导情景记忆检索和记忆编码的神经回路的破坏。

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