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极低出生体重儿发育结局中的家庭因素和社会支持

Family factors and social support in the developmental outcomes of very low-birth weight children.

作者信息

Hogan D P, Park J M

机构信息

Population Studies and Training Center, Brown University, Providence, Rhode Island, USA.

出版信息

Clin Perinatol. 2000 Jun;27(2):433-59. doi: 10.1016/s0095-5108(05)70030-0.

Abstract

This study used data that were representative of the normative population of all infants born in 1988 and were followed during the first 3 years of life. Large developmental delays and limitations in function were common among children weighing less than 1500 g at birth. Among very low-birth weight infants, minority status and living in a household headed by a single mother further worsen the disadvantages associated with a very low birth weight. Nor could the disadvantages associated with very low birth weight be accounted for by controls for other risk factors or buffering statuses and behaviors. Among all children (including those of very low birth weight) poverty, reliance on Medicaid and other government sources for health insurance, a history of risky behaviors, and inadequate prenatal care are the major risk factors for developmental delays, limitations in function, and impairment at birth. State program benefit levels have no obvious effects on child outcomes, taking into account participation in individual programs. An important finding in light of TANF is that maternal work, the use of child care, and the form and cost of child care did not influence developmental delay, limitation in function, or impairment, the outcomes that we were able to measure during the first 3 years of life. TANF eligibility requirements, however, may increase difficulty in obtaining prenatal and other medical services for mothers and children in need--factors shown here to be related strongly to increased risk of low birth weight and developmental delays, limitations, and impairments. Race and ethnicity, poverty status, and family structure are fundamental factors in early child development and function. Minority status, poverty, and single-parent households greatly increase the likelihood that a mother will engage in risky behaviors (smoking, alcohol use, illegal drug use) during pregnancy and receive inadequate prenatal care. Risky behaviors and inadequate prenatal care are the major risk factors for a baby of very low birth weight. When perinatologists first encounter a new patient who is of very low birth weight they often see an infant who is minority, in poverty, and in a single-parent household. Although such children did more poorly in development and function by age 3, the major effects of these variables were through the selectivity of such children into very low birth weight; the direct impact of these factors on development is somewhat muted. This research suggests there are a number of policies that can reduce development delays and functional limitations among children in the United States. Programs that are targeted to a mother and child (such as WIC, AFDC, health insurance coverage, and possibly the more recent TANF programs) significantly reduced the risk an infant will be of very low birth weight. Access and use of adequate prenatal care are essential. Programs designed to combat maternal behaviors that place the fetus at risk (smoking, alcohol, and illegal drug use) can be very successful in reducing the likelihood an infant will be of very low birth weight. An additional payoff from such programs comes after the birth, because even taking into account birth weight, these variables negatively impact on early childhood development and function. Single-parent family structure, race and ethnic minority status, and poverty status also are known to impact on kindergarten readiness, so that we expect a delayed impact of these variables on the child. The strength of this article is the use of normative population data to assess the role of birth weight in child outcome. We examined prenatal risk factors for a baby of very low birth weight, traced the manner by which these selective risks are reflected in the composition of very low-birth weight babies, demonstrated how a very low birth weight was fundamental to delays in development, and identified risk factors and potential buffers in this process. (ABSTRACT TRUNCATED)

摘要

本研究使用的数据代表了1988年出生的所有婴儿的正常人群,并在其生命的前3年进行了跟踪。出生时体重不足1500克的儿童中,发育严重迟缓及功能受限的情况很常见。在极低出生体重儿中,少数族裔身份以及生活在单亲家庭中,会进一步加剧与极低出生体重相关的劣势。极低出生体重相关的劣势也无法通过控制其他风险因素或缓冲状态及行为来解释。在所有儿童(包括极低出生体重儿)中,贫困、依赖医疗补助和其他政府来源的医疗保险、有危险行为史以及产前护理不足,是发育迟缓、功能受限和出生时受损的主要风险因素。考虑到参与各个项目的情况,州项目福利水平对儿童结局没有明显影响。鉴于《贫困家庭临时援助法》(TANF),一个重要发现是,母亲的工作、儿童保育的使用以及儿童保育的形式和成本,并未影响发育迟缓、功能受限或受损情况,这些是我们在生命的前3年能够测量的结局。然而,TANF的资格要求可能会增加有需要的母亲和儿童获得产前及其他医疗服务的难度——此处显示这些因素与低出生体重及发育迟缓、受限和受损风险增加密切相关。种族和族裔、贫困状况以及家庭结构是儿童早期发育和功能的基本因素。少数族裔身份、贫困和单亲家庭极大地增加了母亲在孕期从事危险行为(吸烟、饮酒、使用非法药物)并接受不足产前护理的可能性。危险行为和不足的产前护理是极低出生体重婴儿的主要风险因素。围产医学专家首次接诊极低出生体重的新患者时,常常会看到一个属于少数族裔、贫困且生活在单亲家庭的婴儿。尽管这类儿童在3岁时的发育和功能表现较差,但这些变量的主要影响是通过这类儿童被选择性地纳入极低出生体重群体;这些因素对发育的直接影响有所减弱。这项研究表明,有多项政策可以减少美国儿童的发育迟缓及功能受限情况。针对母亲和儿童的项目(如妇女、婴儿和儿童营养补充计划(WIC)、对有子女家庭的援助计划(AFDC)、医疗保险覆盖范围,可能还有最近的TANF项目)显著降低了婴儿出生时体重极低的风险。获得并使用充足的产前护理至关重要。旨在对抗使胎儿面临风险的母亲行为(吸烟、饮酒和使用非法药物)的项目,在降低婴儿出生时体重极低的可能性方面可能非常成功。这类项目在婴儿出生后还有额外的好处,因为即使考虑到出生体重,这些变量也会对幼儿发育和功能产生负面影响。单亲家庭结构、种族和少数族裔身份以及贫困状况也已知会影响儿童进入幼儿园的准备情况,因此我们预计这些变量会对儿童产生延迟影响。本文的优势在于使用正常人群数据来评估出生体重在儿童结局中的作用。我们研究了极低出生体重婴儿的产前风险因素,追踪了这些选择性风险在极低出生体重婴儿构成中的体现方式,证明了极低出生体重如何对发育迟缓至关重要,并确定了这一过程中的风险因素和潜在缓冲因素。(摘要截选)

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