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缺血性腿部坏疽截肢术后的围手术期及康复结局

Perioperative and rehabilitative outcomes after amputation for ischaemic leg gangrene.

作者信息

Peng C W, Tan S G

机构信息

Department of Surgery, Singapore General Hospital, Singapore.

出版信息

Ann Acad Med Singap. 2000 Mar;29(2):168-72.

Abstract

INTRODUCTION

Amputation of the severely ischaemic leg is often done when limb salvage is not possible or the patient is not fit enough for it. It is therefore important to determine the natural history of these amputees as our understanding of this will have significant impact on decision making. The aim of this study was to determine the early and late morbidity and mortality rates and rehabilitative outcome of these patients with lower limb amputation for end-stage arterial occlusive disease.

MATERIALS AND METHODS

A retrospective study was done on 72 patients with 77 lower limb amputations for critical limb ischaemia (rest pain, gangrene, ischaemic ulcers) from 1993 to 1998 at the Singapore General Hospital.

RESULTS

The mean age of the amputees was 69.7 years. Fifty-one per cent of the patients were male. Forty-five (58%) of the amputations were performed because the limb vasculature was not reconstructable, 12 (16%) because the limbs were too late for salvage and the remaining 20 (26%) because vascular reconstruction failed. Below knee amputations account for 63.6% of all amputations, above knee amputations account for 35.1% and through knee amputations account for 1.3%. Fifteen (19%) of the amputations had wound infection and 8% of amputations required re-amputation at a higher level for wound infection or failure of wound healing. The contralateral amputation rate was 21%. The 30-day mortality for all amputations was 11.1% and the commonest cause was acute myocardial infarction which accounted for 37.5%. Vascular reconstruction did not alter the overall or perioperative mortality rate. Cumulative survival figures showed that at the end of four years, only 38% of all amputees were still alive. 52.5% of amputees were wheelchair-bound, only 15% were household ambulators and 27.5% were community ambulators. Of all the patients with unilateral below knee amputations, 40% could walk out of home while only 20% of unilateral above amputations and 12.5% of bilateral below knee amputations could walk out of home.

CONCLUSION

Early and late rehabilitation after amputation for critical limb ischaemia remain poor and efforts should be made to salvage critically ischaemic limbs wherever possible in patients who are fit enough.

摘要

引言

当肢体挽救不可能实现或患者身体状况不适合时,常常会对严重缺血的下肢进行截肢。因此,确定这些截肢患者的自然病史很重要,因为我们对此的了解将对决策产生重大影响。本研究的目的是确定这些因终末期动脉闭塞性疾病而进行下肢截肢的患者的早期和晚期发病率、死亡率以及康复结局。

材料与方法

对1993年至1998年在新加坡总医院接受77例下肢截肢手术的72例严重肢体缺血(静息痛、坏疽、缺血性溃疡)患者进行了一项回顾性研究。

结果

截肢患者的平均年龄为69.7岁。51%的患者为男性。45例(58%)截肢是因为肢体血管无法重建,12例(16%)是因为肢体挽救为时已晚,其余20例(26%)是因为血管重建失败。膝下截肢占所有截肢的63.6%,膝上截肢占35.1%,膝关节离断占1.3%。15例(19%)截肢出现伤口感染,8%的截肢因伤口感染或伤口愈合失败需要在更高平面再次截肢。对侧截肢率为21%。所有截肢的30天死亡率为11.1%,最常见的原因是急性心肌梗死,占37.5%。血管重建并未改变总体或围手术期死亡率。累积生存数据显示,在四年末,所有截肢患者中只有38%仍存活。52.5%的截肢患者需要依靠轮椅行动,只有15%能够在家中行走,27.5%能够在社区行走。在所有单侧膝下截肢的患者中,40%能够走出家门,而单侧膝上截肢患者中只有20%以及双侧膝下截肢患者中只有12.5%能够走出家门。

结论

严重肢体缺血截肢后的早期和晚期康复情况仍然很差,对于身体状况允许的患者,应尽可能努力挽救严重缺血的肢体。

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