小鼠对鸟分枝杆菌感染的T细胞应答的抗原特异性
Antigen specificity of T-cell response to Mycobacterium avium infection in mice.
作者信息
Pais T F, Cunha J F, Appelberg R
机构信息
Laboratory of Microbiology and Immunology of Infection, Institute for Molecular and Cell Biology, University of Porto, Porto, Portugal.
出版信息
Infect Immun. 2000 Aug;68(8):4805-10. doi: 10.1128/IAI.68.8.4805-4810.2000.
Abstract
T cells from Mycobacterium avium-infected C57BL/6 mice reacted to culture filtrate, envelope, and cytosol proteins and to fractions obtained from these proteins. Multiple targets were recognized, such as 29- to 45-kDa and <21-kDa antigens of the culture filtrate, antigens of around 30 kDa in the envelope and cytosol, and 45- to 116-kDa proteins in the envelope.
摘要
来自感染鸟分枝杆菌的C57BL/6小鼠的T细胞对培养滤液、包膜和胞质溶胶蛋白以及从这些蛋白中获得的组分产生反应。识别出多个靶标，如培养滤液中的29至45 kDa和<21 kDa抗原、包膜和胞质溶胶中约30 kDa的抗原以及包膜中的45至116 kDa蛋白。
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