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[动脉闭塞性疾病患者对卫生和饮食规则的依从性调查]

[Survey on adherence to hygiene and dietary rules in patients with arterial occlusive disease].

作者信息

Aligne C, Mosnier M, Mistretta F, Larguier J S

机构信息

Service d'Angiologie, Centre Médical de Chavanne, 42400 Saint-Chamond, France.

出版信息

J Mal Vasc. 2000 Jun;25(3):187-94.

Abstract

OBJECTIVE

Chronic arterial occlusive disease of the lower limbs, a common (800,000 patients in France) invalidating condition, can involve one or more arterial territories. In 90% of the cases, it is related to a more general disease, atherosclerosis. The risk factors are the same as for atherosclerosis and can be classed into three distinct groups: pathological conditions, constitutional characteristics, and lifestyle. Besides age and gender, smoking habits are by far the most predominant vascular risk factor for chronic arterial occlusive disease. Other factors include diabetes, known to play a particular role in diabetic arteriopathy, generally with more distal and quite severe lesions, high blood pressure, a less evident but certain risk factor, and hyperlipidemia, whole role in the pathogenesis of chronic arterial occlusive disease is well recognized though not predominant. These different data led us to analyze a cohort of patients with chronic arterial occlusive disease of the lower limbs to ascertain the cause of success or failure of hygiene and diet counseling.

PATIENTS AND METHODS

The study protocol included three steps. We first established the profile of a typical arteriopathy patient based on demographic data, history of the arterial disease, personal and familial medical history and lifestyle: smoking habits, physical exercise, diet. The second step was to estimate the proportion of patients following hygiene and dietary rules. Finally, we looked for the reasons why the patients succeeded or failed in following these rules. This cross-sectional study involved 1,500 practitioners. Each physician selected 3 patients, men or women aged 40 to 80 years whose arteriopathy had reached the stage of intermittent claudication. Evaluation criteria were based on the demographic data and conditions of adherence to advice as well as conditions leading to success or failure: personal motivation, familial support, the patient's knowledge of the disease, its pathophysiological mechanisms, and the way the risk factors contribute to its genesis and aggravation.

RESULTS

The sex ratio of the 3,294 recruited patients was 4.3 (2,672 men and 622 women). Disease duration and walking distance were 8.6 +/- 6 years and 418 +/- 297 meters respectively. Thirty-eight percent of the patients had undergone surgery of the lower limbs. One thousand four hundred ninety-four patients (45%) had undergone surgery for their arterial disease (lower limbs, coronary or cerebral arteries). Forty-nine percent were aware of the risk of amputation. Overall adherence to drug therapy was good for 82% of the patients. Patients were treated basically with vasoactive and platelet antiaggregates (95 and 82% of the patients respectively). Seventy-nine percent of the patients were former smokers (38% continued to smoke). Fifty-six percent had a specific regular physical activity compared with 42% prior to their disease. Seventeen percent of the patients had already tried a Mediterranean type diet (with a success rate of 69%). Among the 3, 294 patients, 950 (28.8%) followed hygiene and dietary rules well. The main reasons and/or conditions differentiating those who were successful and those who were not were, for each item: personal motivation, family support, and perception of the influence of lifestyle on disease course. These differences were highly significant (p <0.001).

CONCLUSION

Considering the importance of following good hygiene and dietary rules for secondary prevention of chronic arterial occlusive disease of the lower limbs, it was interesting to assess with precision the percentage of diseased patients who follow such rules. Only about 30% of the patients were successful in correcting all behaviors.

摘要

目的

下肢慢性动脉闭塞性疾病是一种常见的(在法国有80万患者)致残性疾病,可累及一个或多个动脉区域。在90%的病例中,它与一种更普遍的疾病——动脉粥样硬化有关。其危险因素与动脉粥样硬化相同,可分为三个不同的组:病理状况、体质特征和生活方式。除年龄和性别外,吸烟习惯是慢性动脉闭塞性疾病迄今为止最主要的血管危险因素。其他因素包括糖尿病,已知其在糖尿病性动脉病中起特殊作用,通常病变更靠近远端且相当严重;高血压,是一个不太明显但确定的危险因素;以及高脂血症,其在慢性动脉闭塞性疾病发病机制中的作用虽不突出但已得到充分认识。这些不同的数据促使我们分析一组下肢慢性动脉闭塞性疾病患者,以确定卫生和饮食咨询成功或失败的原因。

患者与方法

研究方案包括三个步骤。我们首先根据人口统计学数据、动脉疾病史、个人和家族病史以及生活方式(吸烟习惯、体育锻炼、饮食)建立典型动脉病患者的概况。第二步是估计遵循卫生和饮食规则的患者比例。最后,我们寻找患者遵循这些规则成功或失败的原因。这项横断面研究涉及1500名从业者。每位医生选择3名年龄在40至80岁之间、动脉病已发展到间歇性跛行阶段的患者,男女不限。评估标准基于人口统计学数据、遵循建议的情况以及导致成功或失败的情况:个人动机、家庭支持、患者对疾病及其病理生理机制的了解,以及危险因素对其发生和加重的作用方式。

结果

招募的3294名患者的性别比为4.3(2672名男性和622名女性)。病程和步行距离分别为8.6±6年和418±297米。38%的患者接受过下肢手术。1494名患者(45%)因动脉疾病(下肢、冠状动脉或脑动脉)接受过手术。49%的患者知晓截肢风险。总体而言,82%的患者药物治疗依从性良好。患者主要接受血管活性药物和抗血小板聚集药物治疗(分别为95%和82%的患者)。79%的患者曾吸烟(38%仍在吸烟)。56%的患者有特定的规律体育活动,而患病前这一比例为42%。17%的患者曾尝试地中海式饮食(成功率为69%)。在3294名患者中,950名(28.8%)很好地遵循了卫生和饮食规则。对于每一项内容,区分成功和不成功患者的主要原因和/或条件是:个人动机、家庭支持以及对生活方式对病程影响的认知。这些差异具有高度显著性(p<0.001)。

结论

考虑到遵循良好的卫生和饮食规则对下肢慢性动脉闭塞性疾病二级预防的重要性,精确评估遵循此类规则的患病患者百分比很有意义。只有约30%的患者成功纠正了所有行为。

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