Faust S N, Heyderman R S, Levin M
Department of Paediatrics, Imperial College School of Medicine at St Mary's, Norfolk Place, London, W2 1PG, UK.
Baillieres Best Pract Res Clin Haematol. 2000 Jun;13(2):179-97. doi: 10.1053/beha.2000.0067.
Infection is one of the commonest causes of disseminated intravascular coagulation (DIC). DIC is a complex disorder that results from an imbalance of the pro- and anticoagulant regulatory pathways. This chapter will explain the cellular and molecular basis of the disorder and consider the rationale behind current and experimental treatment strategies.