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采用阿霉素-链脲佐菌素与5-氟尿嘧啶-达卡巴嗪交替联合方案治疗晚期甲状腺髓样癌。降钙素瘤研究组(GETC)。

Treatment of advanced medullary thyroid cancer with an alternating combination of doxorubicin-streptozocin and 5 FU-dacarbazine. Groupe d'Etude des Tumeurs à Calcitonine (GETC).

作者信息

Nocera M, Baudin E, Pellegriti G, Cailleux A F, Mechelany-Corone C, Schlumberger M

机构信息

Service de Médecine Nucléaire et de Cancérologie Endocrinienne, Institute Gustave-Roussy, Villejuif Cedex, 94805, France.

出版信息

Br J Cancer. 2000 Sep;83(6):715-8. doi: 10.1054/bjoc.2000.1314.

Abstract

Combinations of doxorubicin and streptozocin and 5-FU and dacarbazine were given alternately to 20 patients with metastatic medullary thyroid carcinoma. Three partial responses and 10 long-term stabilizations were observed. No unexpected toxicity occurred.

摘要

对20例转移性甲状腺髓样癌患者交替给予阿霉素与链脲霉素、5-氟尿嘧啶和达卡巴嗪联合治疗。观察到3例部分缓解和10例长期病情稳定。未发生意外毒性反应。

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