Callahan C M, Haag K M, Weinberger M, Tierney W M, Buchanan N N, Stump T E, Nisi R
Indiana University Center for Aging Research, Regenstrief Institute for Health Care, Indiana University School of Medicine, Indianapolis 46202-2859, USA.
J Am Geriatr Soc. 2000 Sep;48(9):1048-54. doi: 10.1111/j.1532-5415.2000.tb04779.x.
Percutaneous endoscopic gastrostomy (PEG) has become the preferred method to provide enteral tube feeding to older adults who have difficulty eating, but the impact of PEG on patient outcomes is poorly understood. The objective of this study was to describe changes in nutrition, functional status, and health-related quality of life among older adults receiving PEG.
A prospective cohort study.
A small community of approximately 60,000 residents served by two hospital systems.
One hundred fifty patients aged 60 and older receiving PEG from one of the four gastroenterologists practicing in the targeted community.
Patients were assessed at baseline and every 2 months for 1 year to obtain clinical characteristics, process of care data, physical and cognitive function, subjective health status, nutritional status, complications, and mortality.
Over a 14-month period, 150 patients received PEG tubes in the targeted community; the mean age was 78.9. The most frequent indications for the PEG were stroke (40.7%), neurodegenerative disorders (34.7%), and cancer (13.3%). All measures of functional status, cognitive status, severity of illness, comorbidity, and quality of life demonstrated profound and life-threatening impairment; 30-day mortality was 22% and 1-year mortality was 50%. Among patients surviving 60 days or more, at least 70% had no significant improvement in functional, nutritional, or subjective health status. Serious complications were rare, but most patients experienced symptomatic problems that they attributed to the enteral tube feeding.
PEG tube feeding in severely and chronically ill older adults can be accomplished safely. However, there are important patient burdens associated with the PEG and there was limited evidence that the procedure improves functional, nutritional, or subjective health status in this cohort of older adults. The issues raised in this descriptive study provide impetus for a randomized trial of PEG tube feeding compared with alternative methods of patient care for older adults with difficulty eating.
经皮内镜下胃造口术(PEG)已成为为进食困难的老年人提供肠内管饲的首选方法,但PEG对患者预后的影响尚不清楚。本研究的目的是描述接受PEG的老年人在营养、功能状态和健康相关生活质量方面的变化。
一项前瞻性队列研究。
由两个医院系统服务的一个约6万居民的小社区。
从目标社区执业的四位胃肠病学家之一处接受PEG的150名60岁及以上患者。
在基线时以及之后1年中每2个月对患者进行评估,以获取临床特征、护理过程数据、身体和认知功能、主观健康状况、营养状况、并发症和死亡率。
在14个月期间,目标社区有150名患者接受了PEG管;平均年龄为78.9岁。PEG最常见的适应证是中风(40.7%)、神经退行性疾病(34.7%)和癌症(13.3%)。所有功能状态、认知状态、疾病严重程度、合并症和生活质量指标均显示出严重且危及生命的损害;30天死亡率为22%,1年死亡率为50%。在存活60天或更长时间的患者中,至少70%在功能、营养或主观健康状况方面没有显著改善。严重并发症很少见,但大多数患者经历了他们认为与肠内管饲有关的症状性问题。
在严重和慢性病老年人中进行PEG管饲可以安全完成。然而,PEG会给患者带来重要负担,并且仅有有限的证据表明该手术能改善这组老年人的功能、营养或主观健康状况。这项描述性研究中提出的问题为针对进食困难的老年人进行PEG管饲与其他患者护理方法的随机试验提供了动力。