Abraham-Inpijn L, Vreeken J
Arch Chir Neerl. 1975;27(1):63-8.
In a double-blind study, using matched controls, thrombo-embolic prophylaxis with subcutaneous low-dose heparin was studied in 25 patients admitted for orthopaedic surgery. Deep vein thrombosis (DVT) was detected by clinical assessment and by the 125I-fibrinogen leg-scanning technique. As a control the T-1/2 of the 125I-fibrinogen was measured. Six of the 13 patients in the control group and one in the heparin-treated group developed deep vein thrombosis within the first eight postoperative days.
在一项双盲研究中，采用匹配对照，对25例因骨科手术入院的患者进行了皮下低剂量肝素预防血栓栓塞的研究。通过临床评估和¹²⁵I-纤维蛋白原下肢扫描技术检测深静脉血栓形成（DVT）。作为对照，测定了¹²⁵I-纤维蛋白原的T-1/2。对照组13例患者中有6例，肝素治疗组有1例在术后头8天内发生深静脉血栓形成。
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