Roberts V C, Cotton L T
Br Med J. 1975 Aug 23;3(5981):458-60. doi: 10.1136/bmj.3.5981.458.
The possible benefits of adding a low-dose heparin regimen to the technique of peroperative intermittent calf compression for preventing deep vein thrombosis (D.V.T.) were assessed in a randomized trial in 84 surgical patients. The efficacy of peroperative intermittent calf compression was not enhanced by a low-dose heparin regimen, but neither was it worsened. Age, weight, duration, operation, and malignant disease did not affect the relative effectiveness of the two regimens of prophylaxis. The results confirmed that venous stasis is the principal cause of D.V.T.
在一项针对84例外科手术患者的随机试验中,评估了在术中间歇性小腿按压技术基础上添加低剂量肝素方案预防深静脉血栓形成(D.V.T.)的潜在益处。低剂量肝素方案并未增强术中间歇性小腿按压的疗效,但也未使其恶化。年龄、体重、手术时长、手术类型和恶性疾病均不影响这两种预防方案的相对有效性。结果证实静脉淤滞是深静脉血栓形成的主要原因。