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颗粒物对泰国曼谷每日死亡率的影响。

The impact of particulate matter on daily mortality in Bangkok, Thailand.

作者信息

Ostro B, Chestnut L, Vichit-Vadakan N, Laixuthai A

机构信息

Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, USA.

出版信息

J Air Waste Manag Assoc. 1999 Sep;49(9 Spec No):100-7.

Abstract

Several studies conducted in U.S. cities report an association between acute exposures to particulate matter (PM), usually measured as PM10, and mortality. Evidence of high concentrations of PM10 in Eastern Europe and in large metropolitan areas outside of the United States, such as Mexico City and Bangkok, underscores the need to determine whether these same associations occur outside of the United States. In addition, conducting studies of mortality and air pollution in regions that have distinctly different seasonal patterns than those of the United States provides an effective opportunity to assess the potentially confounding aspects of seasonality. Over the last few years, daily measures of ambient PM10 have been collected in Bangkok, a tropical city of over 6 million people. In this metropolitan area, PM10 consists largely of fine particles generated from diesel- and gasoline-powered automobiles, and from two-stroke motorcycle engines. Our analysis involved the examination of the relationship between PM10 and daily mortality for 1992 through 1995. In addition to counts of daily natural mortality (total mortality net of accidents, homicides, and suicides), the data were compiled to assess both cardiovascular and respiratory mortality, and natural mortality by age group. A multivariate Poisson regression model was used to explain daily mortality while controlling for several covariates including temperature, humidity, day of the week, season, and time. The analysis indicated a statistically significant association between PM10 and all of the alternative measures of mortality. The results suggest a 10-microgram/m3 change in daily PM10 is associated with a 1-2% increase in natural mortality, a 1-2% increase in cardiovascular mortality, and a 3-6% increase in respiratory mortality. These relative risks are generally consistent with or greater than those reported in most studies undertaken in the United States.

摘要

在美国城市进行的几项研究报告称,急性接触颗粒物(PM,通常以PM10衡量)与死亡率之间存在关联。东欧以及美国以外的大城市地区(如墨西哥城和曼谷)PM10浓度很高,这凸显了确定美国以外地区是否也存在同样关联的必要性。此外,在季节性模式与美国明显不同的地区开展死亡率和空气污染研究,为评估季节性可能产生的混杂因素提供了一个有效机会。在过去几年里,曼谷这个拥有600多万人口的热带城市收集了每日环境PM10测量数据。在这个大都市地区,PM10主要由柴油和汽油驱动的汽车以及二冲程摩托车发动机产生的细颗粒物组成。我们的分析涉及研究1992年至1995年期间PM10与每日死亡率之间的关系。除了统计每日自然死亡率(扣除事故、凶杀和自杀后的总死亡率)外,还汇编了数据以评估心血管和呼吸系统死亡率以及按年龄组划分的自然死亡率。使用多元泊松回归模型来解释每日死亡率,同时控制包括温度、湿度、星期几、季节和时间在内的几个协变量。分析表明,PM10与所有替代死亡率指标之间存在统计学上的显著关联。结果表明,每日PM10每变化10微克/立方米,自然死亡率增加1 - 2%,心血管死亡率增加1 - 2% , 呼吸系统死亡率增加3 - 6%。这些相对风险通常与在美国进行的大多数研究报告的风险一致或更高。

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