Utian W H, Begg G, Vinik A I, Paul M, Shuman L
Br J Obstet Gynaecol. 1975 Sep;82(9):755-9. doi: 10.1111/j.1471-0528.1975.tb00718.x.
A double-blind study to compare the effect of 2-Br-alpha-ergocryptine (bromocriptine, CB 154, Sandoz) an ergot alkaloid with chlorotrianisene (Tace, Mer-National) on the inhibition of postpartum lactation was carried out in 38 women. At the dosages selected bromocriptine was more effective than chlorotrianisene in inhibiting lactation. Furthermore, bromocriptine significantly reduced serum prolactin levels to low normal values by the seventh day of treatment, whereas chlorotrianisene did not alter the normal progressive reduction in prolactin post-partum. Neither drug had significant toxic effects.
一项双盲研究对38名女性进行，比较麦角生物碱2-溴-α-麦角隐亭（溴隐亭，CB 154，山德士公司）与氯烯雌醚（泰舒，美国家公司）对产后泌乳抑制的效果。在所选用的剂量下，溴隐亭在抑制泌乳方面比氯烯雌醚更有效。此外，溴隐亭在治疗的第七天将血清催乳素水平显著降低至正常低值，而氯烯雌醚并未改变产后催乳素正常的逐渐降低。两种药物均无明显毒性作用。
