Jacobs S C, Cho E, Dunkin B J, Flowers J L, Schweitzer E, Cangro C, Fink J, Farney A, Philosophe B, Jarrell B, Bartlett S T
Divisions of Urology, General Surgery and Transplantation Surgery, Department of Surgery and Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
J Urol. 2000 Nov;164(5):1494-9.
We determined whether laparoscopic living donor nephrectomy decreases the morbidity of renal donation for the donor, while providing a renal allograft of a quality comparable to that of open donor nephrectomy.
In a 3-year period laparoscopic donor nephrectomy was performed via the transperitoneal approach. We evaluated donor and recipient medical records for preoperative donor characteristics, intraoperative parameters and complications, and postoperative recovery and complications.
Of the 320 laparoscopic donor nephrectomies performed the left kidney was removed in 97.5%. Intraoperative complications, which developed in 10.4% of cases, tended to occur early in the experience and required conversion to open nephrectomy in 5. Average operative time was 31/2 hours and warm ischemia time was 21/2 minutes. As the series progressed, blood loss as well as laparoscopic port size and number decreased but extraction site size remained constant at 7 cm. Urinary retention, prolonged ileus, thigh numbness and incisional hernia were the most common postoperative complications. Postoperative analgesic requirements were low and average hospitalization was 66 hours.
Laparoscopic donor nephrectomy appears to be safe and decreases morbidity in the renal donor. Allograft function is comparable to that in open nephrectomy series. The availability of laparoscopic harvesting may be increasing the living donor volunteer pool.
我们确定腹腔镜活体供肾切除术是否能降低供者肾脏捐献的发病率,同时提供质量与开放性供肾切除术相当的同种异体肾移植。
在3年期间,通过经腹途径实施腹腔镜供肾切除术。我们评估了供者和受者的医疗记录,以了解术前供者特征、术中参数及并发症,以及术后恢复情况和并发症。
在实施的320例腹腔镜供肾切除术中,97.5%切除的是左肾。术中并发症发生率为10.4%,在经验积累早期容易发生,其中5例需要转为开放性肾切除术。平均手术时间为3.5小时,热缺血时间为2.5分钟。随着该系列手术的进展,失血量以及腹腔镜切口大小和数量减少,但取出部位大小保持在7厘米不变。尿潴留、肠梗阻延长、大腿麻木和切口疝是最常见的术后并发症。术后镇痛需求较低,平均住院时间为66小时。
腹腔镜供肾切除术似乎是安全的,且可降低供肾者的发病率。同种异体肾移植功能与开放性肾切除术系列相当。腹腔镜获取供肾可能会增加活体供肾志愿者群体。