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[醛固酮与不同行为类型大鼠细胞质及脑细胞核糖皮质激素受体的结合]

[Binding of aldosterone with cytoplasmic and brain nuclear corticosteroid receptors in rats with various types of behavior].

作者信息

Akimov Iu A

机构信息

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.

出版信息

Izv Akad Nauk Ser Biol. 2000 Sep-Oct(5):636-40.

Abstract

The results are given of in vivo experiments on the binding of (3H)aldosterone to corticosteroid receptors of the cytoplasm and nuclei in the brain structure in rats with different types of behavior. Differences were established in binding (3H)aldosterone to corticosteroid receptors of the hippocampus cytoplasm in the animals with different types of behavior both under the normal conditions and within two weeks after stress. Stress was shown to affect the binding of this hormone to corticosteroid receptors of the brain cytoplasm (without hippocampus and cerebellum). No differences were found in the binding of aldosterone to corticosteroid receptors of the brain nuclei after stress.

摘要

给出了关于(3H)醛固酮与不同行为类型大鼠脑结构中细胞质和细胞核皮质类固醇受体结合的体内实验结果。在正常条件下以及应激后两周内,不同行为类型动物海马细胞质皮质类固醇受体对(3H)醛固酮的结合存在差异。应激被证明会影响该激素与脑细胞质(不包括海马和小脑)皮质类固醇受体的结合。应激后,醛固酮与脑细胞核皮质类固醇受体的结合未发现差异。

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