一名获得性血管性水肿患者的腹腔镜脾切除术
Laparoscopic splenectomy in a patient with acquired angioneurotic edema.
作者信息
Jabbour-Khoury S, Khoury G, Soueide A, Baraka A
机构信息
Department of Anesthesiology, American University of Beirut, Lebanon.
出版信息
JSLS. 2000 Oct-Dec;4(4):305-7.
BACKGROUND
We report the case of a 77-year-old female with acquired angioneurotic edema, C1 esterase inhibitor level = 4mg/dL, who was scheduled to undergo laparoscopic splenectomy.
METHODS
In the operating room, we administered on call 500 units (UI) of C1 esterase inhibitor concentrate intravenously. Intraoperative hemodynamic instability and generalized blood oozing improved following the administration of aprotinin 250000 UI intravenous (IV) drip.
CONCLUSION
We recommend the administration of an antifibrinolytic agent in addition to C1 esterase inhibitor concentrate in patients with acquired angioneurotic edema.
背景
我们报告一例77岁患有获得性血管性水肿的女性病例，其C1酯酶抑制剂水平为4mg/dL，计划接受腹腔镜脾切除术。
方法
在手术室，我们在接到通知后静脉注射了500单位（UI）的C1酯酶抑制剂浓缩物。静脉滴注250000单位（UI）抑肽酶后，术中血流动力学不稳定和全身渗血情况得到改善。
结论
我们建议，对于获得性血管性水肿患者，除给予C1酯酶抑制剂浓缩物外，还应给予抗纤溶药物。
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