Misbah S A, Mapstone N P
Yorkshire Regional Immunology Service, Leeds Teaching Hospitals Trust, Leeds General Infirmary, UK.
J Clin Pathol. 2000 Oct;53(10):750-5. doi: 10.1136/jcp.53.10.750.
Whipple's disease has traditionally been considered to be a rare multisystem disorder dominated by malabsorption. The recent identification of the Whipple's disease bacillus has, using polymerase chain reaction based assays, fueled advances in the investigation, diagnosis, and management of this disease. This leader reviews the aetiology, clinical manifestations, investigation, and treatment of Whipple's disease in the light of this new information.
惠普尔病传统上被认为是一种以吸收不良为主的罕见多系统疾病。最近,通过基于聚合酶链反应的检测方法鉴定出了惠普尔病杆菌,这推动了对该疾病的研究、诊断和治疗取得进展。本述评根据这些新信息,对惠普尔病的病因、临床表现、检查和治疗进行了综述。