肯尼亚多重耐药性伤寒沙门氏菌血清型的基因分型分析
Genotypic analysis of multidrug-resistant Salmonella enterica Serovar typhi, Kenya.
作者信息
Kariuki S, Gilks C, Revathi G, Hart C A
机构信息
Kenya Medical Research Institute, Nairobi, Kenya.
出版信息
Emerg Infect Dis. 2000 Nov-Dec;6(6):649-51. doi: 10.3201/eid0606.000616.
Abstract
We report the emergence in Kenya during 1997-1999 of typhoid fever due to Salmonella enterica serovar Typhi resistant to ampicillin, tetracycline, chloramphenicol, streptomycin, and cotrimoxazole. Genotyping by pulsed-field gel electrophoresis of XbaI-digested chromosomal DNA yielded a single cluster. The multidrug-resistant S. Typhi were related to earlier drug- susceptible isolates but were unrelated to multidrug-resistant isolates from Asia.
摘要
我们报告了1997年至1999年期间在肯尼亚出现的由对氨苄西林、四环素、氯霉素、链霉素和复方新诺明耐药的伤寒沙门氏菌伤寒血清型引起的伤寒热。通过对经XbaI消化的染色体DNA进行脉冲场凝胶电泳进行基因分型，得到了一个单一的聚类。多重耐药的伤寒沙门氏菌与早期的药物敏感分离株有关，但与来自亚洲的多重耐药分离株无关。
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