Friend病毒诱导的白血病的自发消退：与消退型和传统型病毒株的共同感染
Spontaneous regression of friend virus induced leukemia: coinfection with regressing and conventional strains of virus.
作者信息
Furmanski P, Baldwin J, Clymer R, Rich M A
出版信息
Science. 1975 Jan 10;187(4171):72-3. doi: 10.1126/science.1109226.
PMID:1109226
Abstract
Mixtures of friend virus (CFV) and the regressing strain of friend virus (RFV) induce leukemia which regresses. The dominance of the regressing phenotype is solely a function of a threshold dose of RFV. The minimum amount of RFV which induced regression of CFV leukemia is below the titer for induction of friend disease, but does correlate ith the titer of lymphocytic leukemia (helper) activity in the these stocks.
摘要
Friend病毒（CFV）与Friend病毒退行株（RFV）的混合物可诱发白血病，且该白血病会发生退行。退行表型的优势仅仅取决于RFV的阈值剂量。诱导CFV白血病退行所需的RFV最小量低于诱发Friend病的滴度，但与这些毒株中淋巴细胞白血病（辅助）活性的滴度相关。
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