贾第虫病作为一种再度出现的传染病及其人畜共患病潜力。

Giardiasis as a re-emerging infectious disease and its zoonotic potential.

作者信息

Thompson R C

机构信息

WHO Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, Division of Veterinary & Biomedical Sciences, Murdoch University, Western Australia 6150, Murdoch, Australia.

出版信息

Int J Parasitol. 2000 Nov;30(12-13):1259-67. doi: 10.1016/s0020-7519(00)00127-2.

DOI:10.1016/s0020-7519(00)00127-2

PMID:11113253

Abstract

The reasons for considering giardiasis as a re-emerging infectious disease are presented, with emphasis on Giardia infections in child care centres, livestock and pets, and the role of zoonotic transmission. However, the aetiology and control of giardiasis is complicated by the genetic and phenotypic variability of Giardia species infective to mammals. Of particular significance has been the uncertainty about host specificity and the question of zoonotic transmission. The recent application of molecular characterisation procedures based on PCR has made an enormous contribution to an understanding of the genetic structure of Giardia populations, and this is reviewed in the context of the zoonotic transmission and molecular epidemiology of Giardia infections.

摘要

文中阐述了将贾第虫病视为一种再度出现的传染病的原因，重点讨论了儿童保育中心、家畜和宠物中的贾第虫感染情况，以及人畜共患病传播的作用。然而，由于感染哺乳动物的贾第虫物种在遗传和表型上的变异性，贾第虫病的病因学和控制变得复杂。特别重要的是宿主特异性的不确定性以及人畜共患病传播的问题。基于聚合酶链反应（PCR）的分子表征程序的最新应用，为理解贾第虫种群的遗传结构做出了巨大贡献，本文将在贾第虫感染的人畜共患病传播和分子流行病学背景下对此进行综述。