Reid G, Bruce A W, Fraser N, Heinemann C, Owen J, Henning B
Lawson Research Institute, London, Ont., Canada.
FEMS Immunol Med Microbiol. 2001 Feb;30(1):49-52. doi: 10.1111/j.1574-695X.2001.tb01549.x.
We report the first clinical evidence that probiotic lactobacilli can be delivered to the vagina following oral intake. In 10 women with a history of recurrent yeast vaginitis, bacterial vaginosis (BV) and urinary tract infections, strains Lactobacillus rhamnosus GR-1 and Lactobacillus fermentum RC-14 suspended in skim milk and given twice daily for 14 days, were recovered from the vagina and identified by morphology and molecular typing within 1 week of commencement of therapy. In six cases of asymptomatic BV or intermediate BV (based upon Nugent scoring) was resolved within 1 week of therapy.
我们报告了首个关于口服摄入益生菌乳酸杆菌后可抵达阴道的临床证据。在10名有复发性霉菌性阴道炎、细菌性阴道病(BV)和尿路感染病史的女性中,将鼠李糖乳杆菌GR-1株和发酵乳杆菌RC-14株悬浮于脱脂乳中,每日服用两次,持续14天,在治疗开始后1周内从阴道中分离出这些菌株,并通过形态学和分子分型进行鉴定。在6例无症状BV或中间型BV(基于 Nugent评分)患者中,治疗1周内病情得到缓解。