蓝氏贾第鞭毛虫中特定变异体表面蛋白的转换
Variant-specific surface protein switching in Giardia lamblia.
作者信息
Nash T E, Luján H T, Mowatt M R, Conrad J T
机构信息
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
出版信息
Infect Immun. 2001 Mar;69(3):1922-3. doi: 10.1128/IAI.69.3.1922-1923.2001.
Abstract
Surface antigen switching in Giardia lamblia was analyzed using monoclonal antibodies specific for two variant-specific surface proteins (VSPs). Two VSPs were detected on the surface of single trophozoites. Dual expression persisted for 13 h but disappeared at 36 h, as in other parasites that undergo surface antigenic variation.
摘要
使用针对两种变异特异性表面蛋白（VSP）的单克隆抗体分析了蓝氏贾第鞭毛虫的表面抗原转换。在单个滋养体表面检测到两种VSP。双表达持续13小时，但在36小时时消失，这与其他经历表面抗原变异的寄生虫情况相同。
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