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脂质贮积症所致风湿病。II型高脂蛋白血症的关节受累:滑膜细胞线粒体中存在微晶

[Rheumatism caused by lipid thesaurismosis. Articular involvement in hyperlipoproteinemia type II : presence of microcrystals in the mitochondria of synoviocytes].

作者信息

Delbarre F, Laoussadi S, Kahan A, Aubouy G

出版信息

C R Seances Acad Sci D. 1979 Jan 8;288(1):181-4.

PMID:111827
Abstract

For 13 years polyarthritis with specific synovial involvement was observed in a case of type II hyperlipoproteinemia. Microcrystals similar to those described in Gaucher's and Fabry's disease were seen in synovial cytoplasm and mitochondria. These data suggest a microcrystalline pathogenesis for type II hyperlipoproteinemia arthritis as in gout and chondrocalcinosis.

摘要

在一例II型高脂蛋白血症患者中观察到伴有特定滑膜受累的多关节炎长达13年。在滑膜细胞质和线粒体中可见到与戈谢病和法布里病中描述的类似的微晶。这些数据表明,II型高脂蛋白血症关节炎如同痛风和软骨钙质沉着症一样,存在微晶发病机制。

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