Tutty S, Simon G, Ludman E
Group Health Cooperative Center for Health Studies, Seattle, Wash., USA.
Eff Clin Pract. 2000 Jul-Aug;3(4):170-8.
Many clinical and logistical barriers exist in the primary care model for treating adult depression.
To examine the feasibility and clinical effects of a telephone counseling and medication monitoring program for adults starting treatment for depression in primary care.
Pilot study with a contemporaneous control group.
Group Health Cooperative, an HMO serving more than 450,000 persons in western Washington.
Twenty-eight adult primary care patients starting antidepressant treatment (telephone counseling group) were compared with 94 patients receiving usual care (control group).
Telephone counseling participants received written educational materials addressing depression, followed by six weekly counseling and support sessions delivered over the telephone by a master's-level therapist. The intervention used the transtheoretical model of behavioral change and cognitive-behavioral strategies to enhance self-monitoring, self-management, and coping skills.
Telephone interviews and computerized pharmacy and visit records.
Participation rate and retention, Hopkins symptom checklist depression scores, medication adherence and dose thresholds, and visits made for depression treatment.
Ninety-three percent of telephone counseling participants contacted agreed to participate, and 92% completed the intervention. Telephone counseling patients showed significantly lower depressive symptoms than did control group patients at 3-month follow-up (0.89 vs. 1.13) and 6-month follow-up (0.79 vs. 0.95; P = 0.03). Telephone counseling patients were twice as likely to adhere to antidepressant medication with adequate dose thresholds (25% vs. 13%) and half as likely to meet criteria for major depression than were control group patients across time (8% vs. 16%), although these differences were not statistically significant. Total outpatient visits made for depression treatment between groups across time did not differ. Overall program cost per patient was estimated at about $150.
A telephone counseling and medication monitoring intervention was well accepted by adult patients starting treatment for depression in primary care. The intervention seems to significantly improve depression outcomes without affecting the number of visits for treatment of depression.
在初级保健模式中治疗成人抑郁症存在许多临床和后勤方面的障碍。
探讨针对初级保健中开始治疗抑郁症的成年人的电话咨询和药物监测项目的可行性及临床效果。
设立同期对照组的试点研究。
Group Health Cooperative,一家为华盛顿州西部超过45万人提供服务的健康维护组织。
28名开始接受抗抑郁治疗的成年初级保健患者(电话咨询组)与94名接受常规护理的患者(对照组)进行比较。
电话咨询参与者会收到关于抑郁症的书面教育材料,随后由一名硕士水平的治疗师通过电话进行为期六周的咨询和支持。该干预采用行为改变的跨理论模型和认知行为策略来增强自我监测、自我管理和应对技能。
电话访谈以及计算机化的药房和就诊记录。
参与率和留存率、霍普金斯症状清单抑郁评分、药物依从性和剂量阈值,以及因抑郁症治疗而进行的就诊次数。
93% 联系过的电话咨询参与者同意参与,92% 完成了干预。在3个月随访时(0.89对1.13)和6个月随访时(0.79对0.95;P = 0.03),电话咨询患者的抑郁症状明显低于对照组患者。电话咨询患者达到足够剂量阈值的抗抑郁药物依从性是对照组患者的两倍(25% 对13%),且在各个时间段内符合重度抑郁症标准的可能性是对照组患者的一半(8% 对16%),尽管这些差异无统计学意义。各时间段内两组间因抑郁症治疗而进行的门诊总就诊次数没有差异。估计每位患者的总体项目成本约为150美元。
电话咨询和药物监测干预受到初级保健中开始治疗抑郁症的成年患者的广泛接受。该干预似乎能显著改善抑郁症的治疗效果,而不影响抑郁症治疗的就诊次数。