Kachalova A V, Zatsepin T S, Romanova E A, Stetsenko D A, Gait M J, Oretskaya T S
Chemistry Department and Belozersky Institute of Physical Chemical Biology, Moscow State University, Russia.
Nucleosides Nucleotides Nucleic Acids. 2000 Oct-Dec;19(10-12):1693-707. doi: 10.1080/15257770008045453.
Chemical syntheses of 2'-O-(allyloxycarbonyl)methyladenosine, 2'-O-(methoxycarbonyl)methyladenosine and 2'-O-(2,3-dibenzoyloxy)propyluridine 3'-2-cyanoethyl-N,N-diisopropyl phosphoramidite building blocks are described. These monomers were used successfully to incorporate carboxylic acid, 1,2-diol and aldehyde functionalities into synthetic oligonucleotides.