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[牛磺酸对猫骨骼肌中静脉和动脉微血管交换功能及肾上腺素能反应的影响]

[Effect of taurine on the microvessel exchange function and adrenergic response of veins and arteries in the cat skeletal muscle].

作者信息

Kudriashov Iu A, Denisov P I

机构信息

Institute of Experimental Medicine, Russian Acad. Med. Sci, 197376, St. Petersburg, Acad. I. P. Pavlov St., 12.

出版信息

Ross Fiziol Zh Im I M Sechenova. 2001 Jan;87(1):28-36.

Abstract

In cats anesthetized with Uretan and perfused with a constant blood volume, Taurine induced responses of neither arterial nor venous vessels of the skeletal muscle but increased the capillary filtration coefficient without any significant change of the capillary pressure in the skeletal muscle's microvessels. Taurine also increased both the constrictor and the dilatory responses of the arterial and venous vessels. The mechanism of the Taurine effects upon the smooth muscle elements of arteries and veins as well as upon proper mechanisms of capillary pressure control and capillary filtration coefficient, seems to be calcium-dependent.

摘要

在用氨基甲酸乙酯麻醉并以恒定血容量灌注的猫中,牛磺酸既未引起骨骼肌动脉血管也未引起静脉血管的反应,但增加了毛细血管滤过系数,而骨骼肌微血管中的毛细血管压力没有任何显著变化。牛磺酸还增加了动脉和静脉血管的收缩反应和舒张反应。牛磺酸对动脉和静脉平滑肌成分以及对毛细血管压力控制和毛细血管滤过系数的适当机制的作用机制似乎是钙依赖性的。

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