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对霉酚酸酯与环孢素联合治疗有反应的严重顽固性坏疽性脓皮病,并伴有单神经炎。

Severe recalcitrant pyoderma gangrenosum responding to a combination of mycophenolate mofetil with cyclosporin and complicated by a mononeuritis.

作者信息

Gilmour E, Stewart D G

机构信息

Dermatology Department, University Hospital Birmingham NHS Trust, Raddlebarn Road, Selly Oak, Birmingham B29 6JD, UK.

出版信息

Br J Dermatol. 2001 Feb;144(2):397-400. doi: 10.1046/j.1365-2133.2001.04036.x.

Abstract

We describe a 17-year-old boy with severe recalcitrant pyoderma gangrenosum. Healing was achieved with a combination of mycophenolate mofetil and cyclosporin, negative pressure dressings and split-skin grafts. His recovery was complicated by a sciatic nerve palsy, which we believe was caused by direct involvement of the nerve at the level of the sciatic notch.

摘要

我们描述了一名患有严重顽固性坏疽性脓皮病的17岁男孩。通过霉酚酸酯和环孢素联合治疗、负压敷料及分层皮片移植实现了愈合。他的恢复过程因坐骨神经麻痹而复杂化,我们认为这是由坐骨切迹水平的神经直接受累所致。

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