Keberle M, Jenett M, Wittenberg G, Kessler C, Beissert M, Hahn D
Institut für Röntgendiagnostik, Universität Würzburg.
Rofo. 2001 Feb;173(2):133-8. doi: 10.1055/s-2001-10894.
To compare easy-to-perform three-dimensional power Doppler ultrasound (3D PDUS) to color Doppler ultrasound (CDUS) and digital subtraction angiography (DSA) in the assessment of internal carotid artery (ICA) stenoses in patients with severe atherosclerosis.
26 ICA's (7 without stenosis, 4 low-, 4 middle-, and 11 high-grade stenoses) in 13 patients were examined with DSA, CDUS, and 3D PDUS. CDUS and 3D PDUS were performed with a 7.5 MHz standard transducer and a Sonoline Elegra ultrasound machine. The three methods were performed and interpreted by different persons who were not aware of the diagnoses.
Regarding the degree of stenosis correlations between DSA and 3D PDUS were r = 0.98 (p < 0.001), between DSA and CDUS r = 0.97 (p < 0.001), and between CDUS and 3D PDUS r = 0.95 (p < 0.001). Sensitivity and specificity regarding the detection of a high-degree stenosis was 90% and 100% for 3D PDUS, and 100% and 93.3% for CDUS.
Even in cases with severe atherosclerosis, both sonographic methods reveal similar results comparable to DSA. 3D PDUS does not result in a diagnostic improvement on CDUS, however, it does give the new opportunity for complete data storage, reconstruction, and survey presentations.
比较操作简便的三维能量多普勒超声（3D PDUS）与彩色多普勒超声（CDUS）及数字减影血管造影（DSA）在评估严重动脉粥样硬化患者颈内动脉（ICA）狭窄中的应用。
对13例患者的26条颈内动脉（7条无狭窄，4条轻度狭窄，4条中度狭窄，11条重度狭窄）进行DSA、CDUS和3D PDUS检查。使用7.5 MHz标准探头和Sonoline Elegra超声仪进行CDUS和3D PDUS检查。这三种方法由不了解诊断结果的不同人员进行操作和解读。
关于狭窄程度，DSA与3D PDUS之间的相关性r = 0.98（p < 0.001），DSA与CDUS之间r = 0.97（p < 0.001），CDUS与3D PDUS之间r = 0.95（p < 0.001）。3D PDUS检测高度狭窄的敏感性和特异性分别为90%和100%，CDUS分别为100%和93.3%。
即使在严重动脉粥样硬化的病例中，两种超声检查方法的结果与DSA相似。3D PDUS并未在CDUS的基础上带来诊断上的改善，然而，它确实为完整的数据存储、重建和图像展示提供了新的机会。
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