Lee J S, Mendez P A, Douglass H O
Department of Surgery, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.
Surg Endosc. 2000 Jun;14(6):595. doi: 10.1007/s004640020083. Epub 2000 Apr 25.
Benzocaine is a commonly used topical anesthetic present in many over-the-counter preparations. The development of methemoglobinemia, associated with the use of benzocaine, is potentially fatal. Methemoglobinemia remains unresponsive to the administration of oxygen alone and, in fact, results in greater tissue hypoxemia than the usual monitoring techniques indicate. We report two cases of benzocaine-induced methemoglobinemia occurring 3 months apart at the same institution. A brief discussion regarding methemoglobin is presented.
苯佐卡因是许多非处方制剂中常用的局部麻醉剂。与使用苯佐卡因相关的高铁血红蛋白血症的发展可能是致命的。高铁血红蛋白血症仅靠吸氧治疗无效，实际上，它会导致比通常监测技术所显示的更严重的组织低氧血症。我们报告了在同一机构相隔3个月发生的两例苯佐卡因诱发的高铁血红蛋白血症病例。并对高铁血红蛋白进行了简要讨论。
