[伤口愈合评估标准的研究进展]

[Progress on evaluation criterion of wound healing].

作者信息

Huang K, Chen Y L

机构信息

Department of Burn and Plastic Surgery, First Hospital of Yichang, Yichang Hubei, P. R. China 443000.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2001 Mar;15(2):126-9.

PMID:11286162

Abstract

OBJECTIVE

To set up some objective and accurate criteria to evaluate wound healing.

METHODS

Documents about wound healing were reviewed and summarized in detail.

RESULTS

Wound healing rate, wound healing time, histopathology analysis, quantity assay of macrophage, determination of hydroxyproline, proliferation of cell, assay of DNA contents and circle of cells, level of transforming growth factor-alpha, levels of interleukin-1, interleukin-6 and tumor necrosis factor, assay of keratinocyte collagenase-1, level of fibroblast growth factor receptor-1, level of monocyte chemoattractant protein-1 and level of keratinocyte plasminogen activator inhabitor type 2 were selected as the evaluation criteria of wound healing.

CONCLUSION

Wound healing rate, wound healing time and histopathology analysis are direct and efficient criteria of wound healing.

摘要

目的

建立客观准确的伤口愈合评估标准。

方法

详细查阅并总结有关伤口愈合的文献。

结果

选择伤口愈合率、伤口愈合时间、组织病理学分析、巨噬细胞定量检测、羟脯氨酸测定、细胞增殖、DNA含量及细胞周期测定、转化生长因子-α水平、白细胞介素-1、白细胞介素-6和肿瘤坏死因子水平、角质形成细胞胶原酶-1检测、成纤维细胞生长因子受体-1水平、单核细胞趋化蛋白-1水平及角质形成细胞纤溶酶原激活物抑制因子2型水平作为伤口愈合的评估标准。