Schweinfurth J M, Boger G N, Feustel P J
Division of Otolaryngology, Albany Medical Center, Albany, New York, USA.
Head Neck. 2001 May;23(5):376-82. doi: 10.1002/hed.1047.
The presentation and definitive surgical treatment of head and neck malignancies have varying impact on postoperative recovery and return of swallowing function, which heretofore has not been well defined.
We performed a retrospective chart review of 142 patients who underwent extirpative surgery for head and neck cancer.
Factors significantly associated with the need for long-term postoperative nutritional support (p < .05) included heavy alcohol use, tongue base involvement and surgery, pharyngectomy, composite resection, reconstruction with a myocutaneous flap, radiation therapy, tumor size, and moderately-to-poorly differentiated histology. Heavy alcohol users were at an absolute risk for gastrostomy tube dependence; patients who underwent radiation therapy, flap reconstruction, tongue base resection, and pharyngectomy were at a two to sevenfold increased risk for gastrostomy tube dependence, respectively.
High-risk patients based on these criteria should receive a feeding gastrostomy at the time of their initial surgical therapy.
头颈部恶性肿瘤的表现及最终手术治疗方式对术后恢复和吞咽功能的恢复有着不同程度的影响,而这一点至今尚未得到明确界定。
我们对142例行头颈部癌症切除手术的患者进行了回顾性病历审查。
与术后长期营养支持需求显著相关的因素(p < 0.05)包括大量饮酒、舌根受累及手术、咽切除术、联合切除术、肌皮瓣重建、放疗、肿瘤大小以及中低分化组织学类型。大量饮酒者存在胃造瘘管依赖的绝对风险;接受放疗、皮瓣重建、舌根切除术和咽切除术的患者胃造瘘管依赖风险分别增加2至7倍。
基于这些标准的高危患者在初次手术治疗时应接受胃造瘘术。