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晚期胃癌姑息性切除的评估

Evaluation of palliative resection in advanced carcinoma of the stomach.

作者信息

Stern J L, Denman S, Elias E G, Didolkar M, Holyoke E D

出版信息

Surgery. 1975 Feb;77(2):291-8.

PMID:1129702
Abstract

A retrospective study of 140 patients with adenocarcinoma of the stomach seen at Roswell Park Memorial Institute during a 5 year period revealed that 112 patients were TNM Stages III or IV. A palliative resection of the stomach was done in 39 patients; the other 73 did not undergo resection. Patients who had palliative resection for stages III and IV carcinoma of the stomach had a prolonged mean survival rate, as compared with those with similar stage of disease who did not have palliative resection, regardless of an additional treatment such as feeding procedures, gastroenterostomy, chemotherapy, and radiation therapy. This significance was noticed regardless of age, sex, and histological differentiation of the tumor. Chemotherapy significantly increased the survival rate in the unresected group but failed to show this effect in the resected group.

摘要

一项对罗斯威尔公园纪念研究所5年间收治的140例胃腺癌患者的回顾性研究显示,112例患者处于TNM III期或IV期。39例患者接受了胃姑息性切除术;另外73例未接受手术。与疾病分期相似但未接受姑息性切除术的患者相比,接受胃III期和IV期癌姑息性切除术的患者平均生存期延长,无论是否进行了诸如喂养程序、胃肠造口术、化疗和放疗等额外治疗。无论肿瘤的年龄、性别和组织学分化如何,均观察到这一显著意义。化疗显著提高了未切除组的生存率,但在切除组中未显示出这种效果。

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