Botelho R J, DiNicolo L, Tsao N, Karaiskakis A, Tarsounas M, Moens P B, Pearlman R E
Department of Biology, York University, 4700 Keele St., Toronto, Ont., Canada M3J 1P3.
Biochim Biophys Acta. 2001 Apr 16;1518(3):294-9. doi: 10.1016/s0167-4781(01)00171-3.
SYCP3 localizes to the lateral elements of the synaptonemal complex and is essential for male meiosis. The genomic structure of SYCP3 consists of nine exons spanning approximately 14 kb. In mouse and rat, but not in hamster, the putative translation start of SYCP3 is present in the first exon. The putative promoter of SYCP3 was also cloned and shown to drive transcription of a reporter gene in somatic cells.
SYCP3定位于联会复合体的侧生元件，对雄性减数分裂至关重要。SYCP3的基因组结构由9个外显子组成，跨度约为14 kb。在小鼠和大鼠中，SYCP3的推定翻译起始位点存在于第一个外显子中，但在仓鼠中则不存在。SYCP3的推定启动子也已被克隆，并显示可驱动报告基因在体细胞中的转录。
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