Poiraudeau S, Foltz V, Drapé J L, Fermanian J, Lefèvre-Colau M M, Mayoux-Benhamou M A, Revel M
Service de rééducation et de réadaptation de l'appareil locomoteur et des pathologies du rachis, Paris, France.
Rheumatology (Oxford). 2001 Apr;40(4):460-6. doi: 10.1093/rheumatology/40.4.460.
To evaluate the reliability, sensitivity, specificity and positive (PPV) and negative (NPV) predictive values for the diagnosis of sciatica associated with disc herniation of the bell test (BT) and the hyperextension test (HT).
According to magnetic resonance imaging, computed tomography scanning or myelography findings, patients were classified as having sciatica associated with disc herniation (group A) or sciatica without disc herniation or sciatica of other mechanical origin (group B). Four clinical manoeuvres [bell test (BT), hyperextension test (HT), Lasègue's sign (LS) and the crossed Lasègue's sign (CL)] were tested by three investigators. Intra- and interobserver reliabilities were calculated using the kappa correlation coefficient or the intraclass correlation coefficient (ICC). The sensitivity, specificity, PPV and NPV of the four manoeuvres were calculated. Stepwise logistic regression analysis was performed to determine the best set of variables predicting sciatica caused by disc herniation.
Seventy-eight patients (43 in group A, 35 in group B; 33 males) with a mean age of 50+/-16 yr were included. Interobserver reliabilities ranged from 0.58 to 0.64 for the BT, 0.35 to 0.50 for the HT, 0.27 to 0.47 for LS and 0.43 to 0.72 for CL. LS had the best sensitivity (0.77-0.83) and CL the best specificity (0.74-0.89), while PPV and NPV were equivalent for the four manoeuvres (0.55-0.75 for PPV and 0.45-0.59 for NPV). The best PPV was observed for the association of HT with CL (0.67-0.85). Stepwise logistic regression analysis did not allow us to propose a set of variables predicting sciatica caused by disc herniation.
This study suggests that clinical values of the BT and HT are of interest, and are similar to those of LS and CL.
评估钟氏试验(BT)和过伸试验(HT)诊断椎间盘突出症所致坐骨神经痛的可靠性、敏感性、特异性以及阳性预测值(PPV)和阴性预测值(NPV)。
根据磁共振成像、计算机断层扫描或脊髓造影结果,将患者分为椎间盘突出症所致坐骨神经痛组(A组)和非椎间盘突出症或其他机械性病因所致坐骨神经痛组(B组)。三名研究人员对四项临床操作[钟氏试验(BT)、过伸试验(HT)、直腿抬高试验(LS)和交叉直腿抬高试验(CL)]进行检测。采用kappa相关系数或组内相关系数(ICC)计算观察者内和观察者间的可靠性。计算这四项操作的敏感性、特异性、PPV和NPV。进行逐步逻辑回归分析,以确定预测椎间盘突出症所致坐骨神经痛的最佳变量组合。
纳入78例患者(A组43例,B组35例;男性33例),平均年龄50±16岁。观察者间对BT的可靠性范围为0.58至0.64,HT为0.35至0.50,LS为0.27至0.47,CL为0.43至0.72。LS的敏感性最佳(0.77 - 0.83),CL的特异性最佳(0.74 - 0.89),而四项操作的PPV和NPV相当(PPV为(0.55 - 0.75),NPV为(0.45 - )0.59)。HT与CL联合时PPV最佳(0.67 - 0.85)。逐步逻辑回归分析未能让我们提出一组预测椎间盘突出症所致坐骨神经痛的变量。
本研究表明,BT和HT的临床价值值得关注,且与LS和CL的临床价值相似。