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对长期随访的药物滥用治疗研究中的时间效应和结果预测因素的综述。初步结果和方法学问题。

A review of temporal effects and outcome predictors in substance abuse treatment studies with long-term follow-ups. Preliminary results and methodological issues.

作者信息

McKay J R, Weiss R V

机构信息

University of Pennsylvania and DeltaMetrics, USA.

出版信息

Eval Rev. 2001 Apr;25(2):113-61. doi: 10.1177/0193841X0102500202.

Abstract

This article is an initial report from a review of alcohol and drug treatment studies with follow-ups of 2 years or more. The goals of the review are to examine the stability of substance use outcomes and the factors that moderate or mediate these outcomes. Results from 12 studies that generated multiple research reports are presented, and methodological problems encountered in the review are discussed. Substance use outcomes at the group level were generally stable, although moderate within-subject variation in substance use status over time was observed. Of factors assessed at baseline, psychiatric severity was a significant predictor of outcome in the highest percentage of reports, although the nature of the relationship varied. Stronger motivation and coping at baseline also consistently predicted better drinking outcomes. Better progress while in treatment, and the performance of pro-recovery behaviors and low problem severity in associated areas following treatment, consistently predicted better substance use outcomes.

摘要

本文是一项对随访时间达两年或更长时间的酒精和药物治疗研究进行综述的初步报告。该综述的目的是研究物质使用结果的稳定性以及调节或介导这些结果的因素。本文呈现了12项产生多篇研究报告的研究结果,并讨论了综述过程中遇到的方法学问题。尽管观察到个体在物质使用状况上随时间存在适度的内部变化,但群体层面的物质使用结果总体上是稳定的。在基线评估的因素中,精神疾病严重程度在最高比例的报告中是结果的显著预测因素,尽管关系的性质各不相同。基线时更强的动机和应对能力也始终预示着更好的饮酒结果。治疗期间取得更好的进展,以及治疗后在相关领域表现出促进康复的行为和较低的问题严重程度,始终预示着更好的物质使用结果。

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