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[如今应对蜂窝织炎和坏死性筋膜炎需要哪些数据?]

[What data is needed today to deal with cellulitis and necrotizing fasciitis?].

作者信息

Cazorla C

机构信息

Service des Maladies Infectieuses, Hôpital Bellevue, Saint-Etienne, France.

出版信息

Ann Dermatol Venereol. 2001 Mar;128(3 Pt 2):443-51.

Abstract

Cellulitis and necrotizing fasciitis can be distinguished by the depth of the cutaneous lesion and classically by the different bacteria implicated. This classification is not taken into account by the practitioner because of a similar therapeutic strategy. That is why most authors used a single title: necrotizing soft tissue infection. The potential severity of these infections required a quick diagnosis to decrease the risk of mortality and severe functional consequences. The analysis of the literature doesn't allow to establish the incidence of these infections. It was demonstrated that infections due to Streptococcus serogroup A increased over the last few years, thanks to a specific surveillance system. Risk factors leading to these infections are: cutaneous trauma, age, diabetes, varicella in children, contact with people infected by Streptococcus. The most recent studies demonstrated a frequent polymicrobism of the infections, with anaerobes, Streptococcus, Staphylococcus, and gram-negative rods. At the onset of the disease, the diagnosis is difficult to establish. Pain, induration of tissues, a rapid evolution, the inefficacy of antibiotic treatment suggest the diagnosis of necrotizing infection. MRI, when available, is a good technique to reveal the depth of the infection and necrosis. Surgery will confirm the diagnosis and allow for debridement of necrotized tissues. A delayed surgery increases the mortality risk factor, as stated in numerous studies.

摘要

蜂窝织炎和坏死性筋膜炎可通过皮肤病变的深度来区分,传统上也可通过涉及的不同细菌来区分。由于治疗策略相似,从业者并未考虑这种分类。这就是为什么大多数作者使用单一名称:坏死性软组织感染。这些感染的潜在严重性需要快速诊断,以降低死亡风险和严重功能后果的风险。对文献的分析无法确定这些感染的发病率。事实证明,由于特定的监测系统,过去几年中A群链球菌引起的感染有所增加。导致这些感染的风险因素包括:皮肤创伤、年龄、糖尿病、儿童水痘、与感染链球菌的人接触。最近的研究表明,这些感染中常存在多种微生物,包括厌氧菌、链球菌、葡萄球菌和革兰氏阴性杆菌。在疾病初期,诊断很难确立。疼痛、组织硬结、病情迅速发展、抗生素治疗无效提示坏死性感染的诊断。如有条件,MRI是揭示感染和坏死深度的良好技术。手术将确认诊断并允许对坏死组织进行清创。如众多研究所述,延迟手术会增加死亡风险因素。

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