Hser Y I, Hoffman V, Grella C E, Anglin M D
UCLA Drug Abuse Research Center, 1640 S Sepulveda Blvd, Suite 200, Los Angeles, CA 90025, USA.
Arch Gen Psychiatry. 2001 May;58(5):503-8. doi: 10.1001/archpsyc.58.5.503.
This study examined longitudinal patterns of heroin use, other substance use, health, mental health, employment, criminal involvement, and mortality among heroin addicts.
The sample was composed of 581 male heroin addicts admitted to the California Civil Addict Program (CAP) during the years 1962 through 1964; CAP was a compulsory drug treatment program for heroin-dependent criminal offenders. This 33-year follow-up study updates information previously obtained from admission records and 2 face-to-face interviews conducted in 1974-1975 and 1985-1986; in 1996-1997, at the latest follow-up, 284 were dead and 242 were interviewed.
In 1996-1997, the mean age of the 242 interviewed subjects was 57.4 years. Age, disability, years since first heroin use, and heavy alcohol use were significant correlates of mortality. Of the 242 interviewed subjects, 20.7% tested positive for heroin (with additional 9.5% urine refusal and 14.0% incarceration, for whom urinalyses were unavailable), 66.9% reported tobacco use, 22.1% were daily alcohol drinkers, and many reported illicit drug use (eg, past-year heroin use was 40.5%; marijuana, 35.5%; cocaine, 19.4%; crack, 10.3%; amphetamine, 11.6%). The group also reported high rates of health problems, mental health problems, and criminal justice system involvement. Long-term heroin abstinence was associated with less criminality, morbidity, psychological distress, and higher employment.
While the number of deaths increased steadily over time, heroin use patterns were remarkably stable for the group as a whole. For some, heroin addiction has been a lifelong condition associated with severe health and social consequences.
本研究调查了海洛因成瘾者在海洛因使用、其他物质使用、健康状况、心理健康、就业、犯罪参与及死亡率方面的纵向模式。
样本由1962年至1964年期间进入加利福尼亚民事成瘾者项目(CAP)的581名男性海洛因成瘾者组成;CAP是针对依赖海洛因的刑事罪犯的强制戒毒项目。这项为期33年的随访研究更新了之前从入院记录以及1974 - 1975年和1985 - 1986年进行的两次面对面访谈中获得的信息;在1996 - 1997年的最新随访中,284人已死亡,242人接受了访谈。
在1996 - 1997年,接受访谈的242名受试者的平均年龄为57.4岁。年龄、残疾状况、首次使用海洛因后的年限以及大量饮酒是死亡率的显著相关因素。在242名接受访谈的受试者中,20.7%的人海洛因检测呈阳性(另有9.5%拒绝进行尿液检测,14.0%被监禁,无法进行尿液分析),66.9%的人报告使用烟草,22.1%的人每日饮酒,许多人报告使用非法药物(例如,过去一年使用海洛因的比例为40.5%;大麻为35.5%;可卡因为19.4%;快克为10.3%;安非他命为11.6%)。该群体还报告了较高的健康问题、心理健康问题及刑事司法系统参与率。长期戒除海洛因与较少的犯罪行为、发病率、心理困扰以及较高的就业率相关。
虽然随着时间推移死亡人数稳步增加,但该群体整体的海洛因使用模式相当稳定。对一些人来说海洛因成瘾是一种伴随严重健康和社会后果的终身状况。