Mandracchia V J, Nelson S C, Barp E A
Foot and Ankle Clinics, Broadlawns Medical Center, Des Moines, Iowa, USA.
Clin Podiatr Med Surg. 2001 Jan;18(1):55-77.
The intent of this article is to present the current understanding of fracture repair and offer investigative evidence to the use of exogenous growth factors enhancing fracture healing. The authors believe that exogenous growth factors have tremendous clinical applications and will continue to influence bone healing in the future. With the expanding knowledge of the intricate molecular and cellular biology of fracture repair being realized, surgeons will be able to enhance and ensure healing of surgical osteotomies, fractured bone ends, or delayed unions. This field of medicine is continuously growing and the possibilities seem endless.
本文旨在阐述目前对骨折修复的认识,并为使用外源性生长因子促进骨折愈合提供研究证据。作者认为外源性生长因子具有巨大的临床应用价值,且在未来将继续影响骨愈合。随着对骨折修复复杂分子和细胞生物学的认识不断扩展,外科医生将能够促进并确保手术截骨、骨折断端或骨不连的愈合。这一医学领域在持续发展,前景似乎无限广阔。