法国分离出的临床B族链球菌中大环内酯类耐药机制
Mechanisms of macrolide resistance in clinical group B streptococci isolated in France.
作者信息
Fitoussi F, Loukil C, Gros I, Clermont O, Mariani P, Bonacorsi S, Le Thomas I, Deforche D, Bingen E
机构信息
Service de Microbiologie, Hôpital Robert Debré, 75019 Paris, France.
出版信息
Antimicrob Agents Chemother. 2001 Jun;45(6):1889-91. doi: 10.1128/AAC.45.6.1889-1891.2001.
Abstract
Macrolide susceptibility was investigated in clinical group B streptococci obtained from neonates or pregnant women in 2000 in France. Of 490 consecutive isolates, 18% were resistant to erythromycin. The erm(B), erm(A) subclass erm(TR), and mef(A) genes were harbored by 47, 45, and 6% of these strains, respectively. Two isolates did not harbor erm or mef genes.
摘要
2000年在法国，对从新生儿或孕妇中分离出的B族链球菌临床菌株进行了大环内酯类药物敏感性研究。在490株连续分离株中，18%对红霉素耐药。这些菌株中分别有47%、45%和6%携带erm(B)、erm(A)亚类erm(TR)和mef(A)基因。有两株分离株未携带erm或mef基因。
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