Cullen P J
Department of Biochemistry, University of Bristol, BS8 1TD, Bristol, UK.
Curr Biol. 2001 May 1;11(9):R342-4. doi: 10.1016/s0960-9822(01)00189-0.
The debate over whether activated Ras can regulate phosphoinositide-specific phospholipase C (PLC) has been contentious and at times heated. The argument may be resolved by the recent identification of a novel Ras-regulated PLC, but some unexpected properties of this protein are sure to stimulate further controversy.
关于活化的Ras是否能够调节磷酸肌醇特异性磷脂酶C(PLC)的争论一直存在争议,有时甚至很激烈。最近发现的一种新型Ras调节的PLC可能会解决这一争论,但这种蛋白质的一些意外特性肯定会引发进一步的争议。