Manabe T, Nishihara K, Kurokawa Y, Hattanda Y, Toyoshima S, Takeda S, Abe R
Department of Surgery, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-ku, Kitakyushu 802-0077, Japan.
Surg Today. 2001;31(5):450-3. doi: 10.1007/s005950170139.
The occurrence of a collision tumor in the stomach, consisting of adenocarcinoma and malignant lymphoma, is extremely rare. We report herein the case of a patient who had undergone a pancreatoduodenectomy for bile duct cancer 5 year earlier, in whom an ulcerating tumor of the remnant stomach developed and grew rapidly within 5 months. Surgical exploration revealed a tumor in the remnant stomach, multiple liver metastases, and multiple lymph node metastases. Total resection of the remnant stomach was performed, and pathological examination revealed a collision tumor consisting of adenocarcinoma and malignant lymphoma. The patient died of liver metastases and lymph node metastases 7 months after his second operation. The coexistence of both adenocarcinoma and malignant lymphoma of the remnant stomach and the etiology of this unusual combination, never previously reported, is discussed.
胃内同时发生腺癌和恶性淋巴瘤的碰撞瘤极为罕见。我们在此报告一例患者,该患者5年前因胆管癌接受了胰十二指肠切除术,术后残胃出现溃疡性肿瘤,并在5个月内迅速生长。手术探查发现残胃有肿瘤、多发肝转移和多发淋巴结转移。遂行残胃全切除术,病理检查显示为腺癌和恶性淋巴瘤组成的碰撞瘤。患者在第二次手术后7个月死于肝转移和淋巴结转移。本文讨论了残胃同时存在腺癌和恶性淋巴瘤的情况以及这种罕见组合的病因,此前从未有过相关报道。