[Cyclin-dependent kinase 4 inhibitor a and tumor].
作者信息
Gong Z, Fu J
机构信息
Medical Genetics Department, the Second Military Medical University, Shanghai 200433 P. R. China.
出版信息
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001 Jun;18(3):219-21.
PMID:11402455
Abstract
INK4a/ARF locus encodes at least two products, P16(INK4a) and P19(ARF), which are very important in controlling cell-cycle arrest and apoptosis. Many human cancers have been found to be highly related to the mutations at this locus. Here is a review of its structure, function and role in tumor suppression.
摘要
Zotero 插件