Erez E, Tam V K, Williams W H, Kanter K R
Section of Cardiothoracic Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA.
Eur J Cardiothorac Surg. 2001 Jun;19(6):793-6. doi: 10.1016/s1010-7940(01)00677-7.
To evaluate the outcome of aortic root augmentation by the Konno-aortoventriculoplasty technique as part of reoperative aortic valve replacement.
Since 1983, 15 patients, 12 males and three females, had repeat aortic valve replacement (AVR) with concomitant Konno aortoventriculoplasty. Age ranged from 1.2 to 18 years (mean 12.5 years). The underlying anatomic diagnoses were valve and subvalvar aortic stenosis in 11, truncal valve insufficiency in one, endocarditis in one, Shone's complex in one and severe aortic insufficiency associated with a ventricular septal defect in one patient. All patients had had previous AVR. The causes for reoperation were prosthetic valve stenosis due to growth in ten and paravalvular leak in one, homograft failure in two, xenograft failure in one, and left ventricular outflow tract obstruction (LVOTO) after mitral valve replacement in one patient. The mean size of explanted prostheses was 19.2 mm (13-23 mm) while the mean size of the implanted prostheses was 24.3 mm (19-27 mm) (P<0.01). Previous aortic root enlargement had been performed in 11 patients in conjunction with AVR. The Manougian technique was used previously in two, Konno aortoventriculoplasty in eight, and both techniques in one patient. The newly implanted aortic valves were a homograft in one patient and mechanical prostheses in 14 patients.
There was one operative death (1 of 15 or 6.6%) in a 17.5 year old patient with previous AVR and posterior root enlargement, due to low cardiac output state. Follow-up ranged from 6 months to 17 years (mean 7.2 years). The only late death occurred in an 11.6-year-old patient due to prosthetic valve endocarditis. Two patients had complete heart block and had permanent pacemaker insertion (2 of 15 or 13.3%). One patient had pulmonary valve replacement because of combined stenosis and insufficiency 5 years after operation. All 13-surviving patients are asymptomatic at latest follow up.
Konno aortoventriculoplasty with repeat AVR may be safely performed. Excellent results may be achieved despite previous aortic root enlargement. It is a good surgical option for complex LVOTO and may even reduce reoperation in children by allowing placement of a larger prosthesis.
评估采用Konno主动脉心室成形术进行主动脉根部扩大术作为再次主动脉瓣置换术一部分的效果。
自1983年以来,15例患者(12例男性和3例女性)接受了再次主动脉瓣置换术(AVR)并同期进行Konno主动脉心室成形术。年龄范围为1.2至18岁(平均12.5岁)。潜在的解剖学诊断为11例瓣膜及瓣下主动脉狭窄、1例干下瓣膜关闭不全、1例心内膜炎、1例Shone综合征以及1例重度主动脉瓣关闭不全合并室间隔缺损。所有患者均曾接受过AVR。再次手术的原因包括10例因生长导致人工瓣膜狭窄、1例瓣周漏、2例同种异体移植物衰竭、1例异种移植物衰竭以及1例二尖瓣置换术后左心室流出道梗阻(LVOTO)。取出的人工瓣膜平均尺寸为19.2 mm(13 - 23 mm),而植入的人工瓣膜平均尺寸为24.3 mm(19 - 27 mm)(P<0.01)。11例患者在AVR的同时曾进行过主动脉根部扩大术。之前2例患者采用了Manougian技术,8例采用了Konno主动脉心室成形术,1例患者两种技术都使用过。新植入的主动脉瓣1例为同种异体移植物,14例为机械瓣膜。
1例17.5岁曾接受过AVR及后根部扩大术的患者因低心排血量状态在手术中死亡(15例中的1例,即6.6%)。随访时间为6个月至17年(平均7.2年)。唯一的晚期死亡发生在1例11.6岁的患者,死于人工瓣膜心内膜炎。2例患者发生完全性心脏传导阻滞并植入了永久性起搏器(15例中的2例,即13.3%)。1例患者在术后5年因合并狭窄和关闭不全接受了肺动脉瓣置换术。在最近一次随访时,所有13例存活患者均无症状。
Konno主动脉心室成形术联合再次AVR可以安全地进行。尽管之前进行过主动脉根部扩大术,仍可取得良好效果。对于复杂的LVOTO,这是一种很好的手术选择,甚至可能通过允许植入更大的人工瓣膜减少儿童再次手术的需求。