Skirving D J, Dan N G
Department of Neurosurgery, Concord Repatriation General Hospital, University of Sydney, Australia.
J Neurosurg. 2001 Jun;94(6):913-7. doi: 10.3171/jns.2001.94.6.0913.
The aim of this study was to investigate outcomes and complication rates associated with percutaneous balloon compression (PBC) of the trigeminal ganglion over a long follow-up period.
This retrospective review was conducted in 496 patients with typical symptoms of unilateral trigeminal neuralgia who underwent 531 PBCs of the trigeminal ganglion between 1980 and 1999. The mean length of follow up was 10.7 years. The treatment used was a modification of that first described by Mullan and Lichtor in 1983. There were nine technical failures. Of the 522 successful procedures, prompt pain relief ensued in all patients except one. Recurrence of pain was found in 95 patients (19.2%) within 5 years and in 158 patients (31.9%) over the entire study period. Symptomatic dysesthesias occurred in 19 patients (3.8%), but corneal anesthesia and anesthesia dolorosa did not.
In this review the authors present data on the largest cohort of patients with the longest follow up for this procedure in the current literature. The balance between the recurrence rate and troublesome sensory complications achieved in this series is favorable when compared with previously published studies on outcomes of PBC and the two alternative percutaneous methods, radiofrequency thermocoagulation and glycerol rhizolysis. The PBC procedure has additional advantages in that it is relatively straightforward and quick, and can be performed during a brief period of general anesthesia with no discomfort to the patient. This makes it an attractive first choice in the treatment of trigeminal neuralgia.
本研究旨在调查三叉神经节经皮球囊压迫术(PBC)在长期随访期间的疗效及并发症发生率。
对496例单侧三叉神经痛典型症状患者进行回顾性研究,这些患者在1980年至1999年间接受了531次三叉神经节PBC治疗。平均随访时间为10.7年。采用的治疗方法是对1983年Mullan和Lichtor首次描述的方法进行改良。有9例技术失败。在522例成功手术中,除1例患者外,所有患者均迅速缓解疼痛。95例患者(19.2%)在5年内出现疼痛复发,158例患者(31.9%)在整个研究期间出现疼痛复发。19例患者(3.8%)出现症状性感觉异常,但未出现角膜麻醉和痛性麻木。
在本综述中,作者提供了当前文献中该手术随访时间最长、患者队列最大的数据。与先前发表的关于PBC以及另外两种经皮治疗方法——射频热凝术和甘油神经根溶解术的疗效研究相比,本系列研究中实现的复发率与棘手的感觉并发症之间的平衡是有利的。PBC手术还有其他优点,即相对简单快捷,可在短暂全身麻醉期间进行,患者无不适感。这使其成为治疗三叉神经痛颇具吸引力的首选方法。