Kalichman S C, Rompa D, Cage M, DiFonzo K, Simpson D, Austin J, Luke W, Buckles J, Kyomugisha F, Benotsch E, Pinkerton S, Graham J
Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Am J Prev Med. 2001 Aug;21(2):84-92. doi: 10.1016/s0749-3797(01)00324-5.
As many as one in three HIV-positive people continue unprotected sexual practices after learning that they are HIV infected. This article reports the outcomes of a theory-based intervention to reduce risk of HIV transmission for people living with HIV infection.
Men (n=233) and women (n=99) living with HIV-AIDS were randomly assigned to receive either (1) a five-session group intervention focused on strategies for practicing safer sexual behavior, or (2) a five-session, contact-matched, health-maintenance support group (standard-of-care comparison). Participants were followed for 6 months post-intervention.
The intervention to reduce risk of HIV transmission resulted in significantly less unprotected intercourse and greater condom use at follow-up. Transmission-risk behaviors with non-HIV-positive sexual partners and estimated HIV transmission rates over a 1-year horizon were also significantly lower for the behavioral risk-reduction intervention group.
This study is among the first to demonstrate successful HIV-transmission risk reduction resulting from a behavioral intervention tailored for HIV-positive men and women.
多达三分之一的艾滋病毒呈阳性者在得知自己感染艾滋病毒后仍继续进行无保护的性行为。本文报告了一项基于理论的干预措施的结果,该措施旨在降低艾滋病毒感染者的艾滋病毒传播风险。
将233名感染艾滋病毒-艾滋病的男性和99名感染艾滋病毒-艾滋病的女性随机分为两组,一组接受为期五节的小组干预,重点是采取更安全性行为的策略;另一组接受为期五节的、接触匹配的健康维护支持小组干预(作为对照标准)。干预结束后对参与者进行了6个月的随访。
降低艾滋病毒传播风险的干预措施在随访时导致无保护性行为显著减少,避孕套使用率更高。行为风险降低干预组与非艾滋病毒阳性性伴侣的传播风险行为以及1年期间的估计艾滋病毒传播率也显著更低。
本研究是首批证明针对艾滋病毒阳性男性和女性量身定制的行为干预成功降低艾滋病毒传播风险的研究之一。