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同步性肝细胞癌和食管癌的外科治疗:病例报告及文献复习

Surgical treatment of synchronous hepatocellular and esophageal carcinoma: case report and review of literature.

作者信息

Pelloni A, Guerra A, Gertsch P

机构信息

Department of Surgery, Ospedale San Giovanni, Bellinzona, Switzerland.

出版信息

Hepatogastroenterology. 2001 May-Jun;48(39):684-6.

Abstract

Simultaneous presentation of hepatocellular carcinoma and esophageal carcinoma is rare. Few cases have been reported as surgically curable. We treated a caucasian man of 68 years who presented a voluminous hepatocellular carcinoma in the right lobe of the liver and a superficial squamous cell carcinoma of the middle third of the esophagus. Both tumors seemed curable with surgery. We adopted a treatment consisting of two steps: 1) curative hepatic right trisegmentectomy; 2) three months later transhiatal esophagectomy. Two units of blood were transfused for both operations. Simultaneous hepatectomy and esophagectomy have been published in seven cases. We opted for resecting the tumors in two distinct procedures to lower the operative risk. Because of the large size of the hepatocellular carcinoma and the small size of the esophageal carcinoma, hepatectomy was performed first. The delay between the two interventions did not compromise the prognosis that is actually dependent of the hepatocellular carcinoma.

摘要

肝细胞癌和食管癌同时出现的情况较为罕见。鲜有病例报道可通过手术治愈。我们治疗了一名68岁的白种男性,他在肝脏右叶出现了巨大的肝细胞癌,同时在食管中三分之一处出现了浅表鳞状细胞癌。两种肿瘤似乎都可通过手术治愈。我们采取了分两步的治疗方法:1)根治性右半肝三叶切除术;2)三个月后经裂孔食管切除术。两次手术均输注了两个单位的血液。同时进行肝切除术和食管切除术的病例已报道过7例。我们选择分两个不同步骤切除肿瘤以降低手术风险。由于肝细胞癌体积较大而食管癌体积较小,所以先进行了肝切除术。两次手术之间的间隔并未影响预后,而预后实际上取决于肝细胞癌。

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