A novel modified pterin from a Eudistoma species ascidian.
作者信息
Van Wagoner R M, Jompa J, Tahir A, Ireland C M
机构信息
Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah 84112, USA.
出版信息
J Nat Prod. 2001 Aug;64(8):1100-1. doi: 10.1021/np010127h.
PMID:11520239
Abstract
The MeOH extract of an Indonesia Eudistoma sp. ascidian contained 1,3,O(7)-trimethylisoxanthopterin (1), a novel pteridine. The purification of 1 was achieved through flash C(18) chromatography and cyano HPLC. The structure was determined primarily through the use of (1)H-(13)C and (1)H-(15)N HMBC measurements and comparison with data obtained for 1,3,7-trimethylguanine (2).
摘要
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