玻璃体内注射结晶皮质醇作为糖尿病性黄斑水肿的辅助治疗
Intraocular injection of crystalline cortisone as adjunctive treatment of diabetic macular edema.
作者信息
Jonas J B, Söfker A
机构信息
Department of Ophthalmology and Eye Hospital, Faculty of Clinical Medicine Mannheim, University of Heidelberg, Heidelberg, Germany.
出版信息
Am J Ophthalmol. 2001 Sep;132(3):425-7. doi: 10.1016/s0002-9394(01)01010-8.
PURPOSE
To report the clinical outcome of a diabetic patient with macular edema treated with an intravitreal injection of crystalline cortisone.
METHODS
Interventional case report. A 73-year-old patient with diabetes mellitus presented with clinically significant diffuse macular edema caused by nonproliferative diabetic retinopathy. Despite grid laser coagulation in the macular region, cystoid macular edema progressed, and within 6 months before the cortisone injection, visual acuity declined from 0.25 to 0.16 and, finally, to 0.10. The patient received a single intravitreal injection of triamcinolone acetonide with topical anesthesia.
RESULTS
After the intravitreal injection of triamcinolone acetonide, visual acuity improved from 0.10 to 0.40 during the follow-up period spanning 5 months. Intraocular pressure increased to values up to 30 mm Hg before antiglaucomatous treatment.
CONCLUSION
Intravitreal injection of triamcinolone acetonide may be useful for treatment of diabetic macular edema resistant to conventional therapy.
目的
报告玻璃体内注射结晶皮质醇治疗糖尿病性黄斑水肿患者的临床结果。
方法
介入性病例报告。一名73岁糖尿病患者因非增殖性糖尿病视网膜病变出现具有临床意义的弥漫性黄斑水肿。尽管在黄斑区进行了格栅样激光光凝，但黄斑囊样水肿仍进展，在注射皮质醇前6个月内，视力从0.25下降至0.16，最终降至0.10。患者在表面麻醉下接受了单次玻璃体内注射曲安奈德。
结果
在玻璃体内注射曲安奈德后，在为期5个月的随访期间，视力从0.10提高至0.40。在进行抗青光眼治疗前，眼压升高至30 mmHg。
结论
玻璃体内注射曲安奈德可能对常规治疗抵抗的糖尿病性黄斑水肿有效。
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