Masuda Y
Department of Anesthesiology, Showa University School of Medicine.
Nihon Rinsho. 2001 Sep;59(9):1722-6.
Trigeminal neuralgia is a disease affecting older individuals. The clinical hallmark of trigeminal neuralgia is a sudden, excruciating paroxysm of pain in the area of the trigeminal nerve. Drug therapy is considered the first line of treatment for trigeminal neuralgia. Anticonvulsant carbamazepine has been used. If relevant pharmacotherapy has been tried without any effect, other procedures are selected. These procedures are microvascular decompression(a radical technique), glycerol trigeminal rhizotomy, percutaneous trigeminal nerve decompression and nerve block. Nerve block with neurolytic solutions and radiofrequency thermocoagulation is a simple, less invasive therapy. In order to avoid hypesthesia and dysesthesia, nerve block using a high concentration of local anesthetics is recommended. In recent years, stereotactic radiosurgery for trigeminal neuralgia has emerged as a new therapeutic modality.
三叉神经痛是一种多见于老年人的疾病。三叉神经痛的临床特征是三叉神经分布区域突发的、剧痛性发作。药物治疗被认为是三叉神经痛的一线治疗方法。已使用抗惊厥药物卡马西平。如果尝试了相关药物治疗但没有任何效果,则选择其他治疗方法。这些方法包括微血管减压术(一种根治性技术)、甘油三叉神经感觉根切断术、经皮三叉神经减压术和神经阻滞。使用神经溶解溶液和射频热凝的神经阻滞是一种简单、侵入性较小的治疗方法。为避免感觉减退和感觉异常,建议使用高浓度局部麻醉剂进行神经阻滞。近年来,立体定向放射外科已成为三叉神经痛的一种新治疗方式。