Mohr P E
Project HOPE Center for Health Affairs, Bethesda, MD 20814, USA.
Adv Ren Replace Ther. 2001 Oct;8(4):273-9. doi: 10.1053/jarr.2001.27592.
Research suggests that daily hemodialysis improves clinical outcomes and patient quality of life when compared with conventional hemodialysis; however, little is known about its economic impact. In this article, we review the literature on the costs of daily hemodialysis (n = 170). We also present updated results from an economic model we constructed that compares 1-year treatment costs for short daily in-center, short daily at-home, nocturnal, and conventional hemodialysis. Clinical parameters for the model were drawn from our review of the clinical literature. Resource use during daily hemodialysis was modeled after the experience of 2 ongoing programs in the United States, a short daily program in California (n = 26) and a nocturnal program in Virginia (n = 13). Reports from the literature and our economic model suggest daily hemodialysis might provide better outcomes and savings when compared with conventional hemodialysis. However, larger, longer controlled studies are needed to see if daily dialysis fulfills these promises. We discuss several issues researchers should keep in mind in designing future studies about the economics of daily dialysis.
研究表明,与传统血液透析相比,每日血液透析可改善临床结局和患者生活质量;然而,其经济影响却鲜为人知。在本文中,我们回顾了关于每日血液透析成本的文献(n = 170)。我们还展示了我们构建的一个经济模型的最新结果,该模型比较了短期每日中心内血液透析、短期每日家庭血液透析、夜间血液透析和传统血液透析的1年治疗成本。该模型的临床参数取自我们对临床文献的回顾。每日血液透析期间的资源使用情况是根据美国正在进行的两个项目的经验建模的,一个是加利福尼亚的短期每日项目(n = 26),另一个是弗吉尼亚的夜间项目(n = 13)。文献报告和我们的经济模型表明,与传统血液透析相比,每日血液透析可能会带来更好的结局和成本节约。然而,需要更大规模、更长时间的对照研究来确定每日透析是否能兑现这些承诺。我们讨论了研究人员在设计未来关于每日透析经济学的研究时应牢记的几个问题。